Adrenocorticotropin (ACTH) in Chronic Pain

Calcium ion as a second messenger for o-nitrophenylsulfenyl-adrenocorticotropin (NPS-ACTH) and ACTH in bovine adrenal steroidogenesis.

o-Nitrophenyl sulfenyl-modified ACTH (NPS-ACTH) stimulated steroidogenesis acutely in bovine fasciculata-reticularis cells without increase in cellular cAMP synthesis. Application of NPS-ACTH to the cultured cells induced Ca2+ signals in individual cells as detected by video-enhanced microscopic fluorescence measurements. The percentage of Ca2+ signaling cells corresponded well with the increas...

Plasma Adrenocorticotropin (ACTH) Values and Cortisol Response to 250 and 1 g ACTH Stimulation in Patients with Hyperthyroidism before and after Carbimazole Therapy: Case-Control Comparative Study

Effectiveness of exercise therapy in reducing pain and disability in athletes with chronic nonspecific neck pain

Aims and background: Chronic neck pain is a common problem and is often associated with changes in sensory-motor functions such as decreased neck proprioception, altered neck muscle coordination, and increased postural fluctuations. The aim of this study was the effectiveness of exercise therapy in improving chronic non-specific neck pain in athletes in Khorramabad. Methods and Materials: The ...

Prediction of Chronic Pain Components based on Mentalization, Emotion Regulation and Empathy in Patients with Chronic Pain

Background and Aim: Chronic pain is one of the most common issues that has encouraged the military population to seek medical care. This study aimed was to predict the components of chronic pain based on empathy, mentalization, and emotion regulation in patients with chronic pain. Methods: The study was a descriptive correlational study and the statistical population was all patients with chron...

Differential expression of somatostatin and dopamine receptor subtype genes in adrenocorticotropin (ACTH)-secreting pituitary tumors and silent corticotroph adenomas.

Somatostatin analogs and dopamine agonists are clinically used for medical therapy of functioning pituitary tumors, such as growth hormone- and prolactin-secreting tumors, however, their effects on ACTH-secreting tumors are controversial. This study was aimed to determine whether somatostatin receptor (SSTR) subtype (1-5) and dopamine receptor type 2 (D2R) are differentially expressed in pituit...